MolNFT v1 · #41444 · protein
Discovery and optimization of a natural HIV-1 entry inhibitor targeting the GP41 fusion peptide
2JNR · VIR165: “Discovery and optimization of a natural HIV-1 entry inhibitor targeting the GP41 fusion peptide”. Solution nmr. MolNFT v1 #41444 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2JNR
- Type
- protein
- Length
- 43 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- VIR165; Env polyprotein
- UniProt
- Q72502
Structure
solution nmr · 2 distinct chains · 0% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | VIR165 | protein | 20 | 0% helix, 0% strand | — |
| B | Env polyprotein | protein | 23 | 0% helix, 0% strand | Q72502 |
Interfaces
1 interface between chains.
- A–B · 467 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 2JNR · Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q72502
- Elsewhere: RCSB PDB 2JNR · PDBe 2JNR · UniProt Q72502
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