MolNFT v1 · #41405 · protein
Solution structure of V7R mutant of HIV-1 myristoylated matrix protein
2JMG · Gag polyprotein: “Solution structure of V7R mutant of HIV-1 myristoylated matrix protein”. Solution nmr, 1 ligand (MYR), 2 pockets (best druggability 0.54). MolNFT v1 #41405 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2JMG
- Type
- protein
- Length
- 131 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Gag polyprotein
- UniProt
- Q72497
- Ligands
- MYR
- Pockets
- 2 · best druggability 0.54
Structure
solution nmr · 1 distinct chain · 61% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Gag polyprotein | protein | 131 | 61% helix, 2% strand | Q72497 |
Ligands and binding sites
- MYR · Myristic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 125 | 0.54 | 0.82 | 23 | MYR |
| 2 | 55 | 0.32 | 0.77 | 11 | empty |
Modifications
Observed in the structure: 1 lipid (myristoylation).
Compared structures
- 2JMG · Solution structure of V7R mutant of HIV-1 myristoylated matrix protein · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q72497
- Elsewhere: RCSB PDB 2JMG · PDBe 2JMG · UniProt Q72497
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