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MolNFT v1 · #41324 · protein

Structure of human signal regulatory protein (sirp) gamma

2JJW · Signal regulatory protein gamma: “Structure of human signal regulatory protein (sirp) gamma”. X-ray diffraction, 1 pocket (best druggability 0.36). MolNFT v1 #41324 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
2JJW
Type
protein
Length
111 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Signal regulatory protein gamma
UniProt
Q9P1W8
Pockets
1 · best druggability 0.36

Structure

x-ray diffraction · 1 distinct chain · 3% helix, 42% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASignal regulatory protein gammaprotein1113% helix, 42% strandQ9P1W8

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1710.360.7717empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

  • 2JJW · Structure of human signal regulatory protein (sirp) gamma · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9P1W8 · AlphaFold monomer V2.0 prediction for signal-regulatory protein gamma (Q9P1W8) · a predicted model of the same protein · chain A against A, TM-score 0.98

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