MolNFT v1 · #41298 · protein

Crystal structure of the putative carbohydrate recognition domain of the human galectin-related protein

2JJ6: “Crystal structure of the putative carbohydrate recognition domain of the human galectin-related protein”. X-ray diffraction, 3 pockets (best druggability 0.62). MolNFT v1 #41298 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 2JJ6
Type: protein
Length: 267 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Galectin-related protein
UniProt: Q3ZCW2
Pockets: 3 · best druggability 0.62

Structure

x-ray diffraction · 2 distinct chains · 2% helix, 52% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Galectin-related protein	protein	134	2% helix, 52% strand	Q3ZCW2
B	Galectin-related protein	protein	133	2% helix, 51% strand	Q3ZCW2

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	267	0.62	0.80	30	empty
2	59	0.33	0.77	16	empty
3	56	0.28	0.74	20	empty

Interfaces

1 interface between chains.

A–B · 288 Å² buried · 1 hydrogen bond · protein-protein

Compared structures

2JJ6 · Crystal structure of the putative carbohydrate recognition domain of the human… · the same entry in another collection · chain A against A, TM-score 1.00
Q3ZCW2 · AlphaFold monomer V2.0 prediction for galectin-related protein (Q3ZCW2) · a predicted model of the same protein · chain B against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q3ZCW2
Elsewhere: RCSB PDB 2JJ6 · PDBe 2JJ6 · UniProt Q3ZCW2

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