MolNFT v1 · #41224 · protein
X-ray crystal structure of a cohesin-like module from clostridium perfringens
2JH2 · O-glcnacase nagj: “X-ray crystal structure of a cohesin-like module from clostridium perfringens”. X-ray diffraction, 3 pockets (best druggability 0.52). MolNFT v1 #41224 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2JH2
- Type
- protein
- Length
- 397 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- O-glcnacase nagj
- UniProt
- Q0TR53
- Pockets
- 3 · best druggability 0.52
Structure
x-ray diffraction · 3 distinct chains · 0% helix, 67% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | O-glcnacase nagj | protein | 133 | 0% helix, 69% strand | Q0TR53 |
| B | O-glcnacase nagj | protein | 134 | 0% helix, 69% strand | Q0TR53 |
| C | O-glcnacase nagj | protein | 130 | 0% helix, 62% strand | Q0TR53 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 330 | 0.52 | 0.73 | 47 | empty |
| 2 | 69 | 0.35 | 0.77 | 26 | empty |
| 3 | 70 | 0.31 | 0.75 | 15 | empty |
Interfaces
2 interfaces between chains.
- A–B · 486 Ų buried · 5 hydrogen bonds · protein-protein
- B–C · 157 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 2JH2 · X-ray crystal structure of a cohesin-like module from Clostridium perfringens · the same entry in another collection · chain A against A, TM-score 1.00
- Q0TR53 · AlphaFold monomer V2.0 prediction for O-glcnacase nagj (Q0TR53) · a predicted model of the same protein · chain C against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q0TR53
- Elsewhere: RCSB PDB 2JH2 · PDBe 2JH2 · UniProt Q0TR53
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