MolNFT v1 · #41025 · protein

Universal stress protein RV2623 from mycobaterium tuberculosis

2JAX · Hypothetical protein TB31.7: “Universal stress protein RV2623 from mycobaterium tuberculosis”. X-ray diffraction, 2 ligands (ATP, UNX), 3 pockets (best druggability 0.66). MolNFT v1 #41025 on GenesisL1: 3D structure, binding sites…

PDB: 2JAX
Type: protein
Length: 261 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hypothetical protein TB31.7
UniProt: O06189
Ligands: ATP, UNX
Pockets: 3 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hypothetical protein TB31.7	protein	261	39% helix, 16% strand	O06189

Ligands and binding sites

ATP · Adenosine-5'-triphosphate · ligand · 2 copies · chains A
UNX · Unknown atom or ion · ion · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	142	0.66	0.88	24	ATP, UNX
2	188	0.56	0.80	33	ATP, UNX
3	114	0.38	0.74	18	empty

Modifications

Observed in the structure: 4 modified, 1 covalent (engineered, covalent ligand).

Compared structures

2JAX · Universal Stress Protein Rv2623 from Mycobaterium Tuberculosis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O06189
Elsewhere: RCSB PDB 2JAX · PDBe 2JAX · UniProt O06189

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