MolNFT v1 · #41001 · protein

Structure of the N-terminal deletion of yeast exosome component RRP40

2JA9 · Exosome complex exonuclease RRP40: “Structure of the N-terminal deletion of yeast exosome component RRP40”. X-ray diffraction, 1 pocket (best druggability 0.29). MolNFT v1 #41001 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 2JA9
Type: protein
Length: 175 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Exosome complex exonuclease RRP40
EC: 3.1.13.-
UniProt: Q08285
Pockets: 1 · best druggability 0.29

Structure

x-ray diffraction · 1 distinct chain · 25% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Exosome complex exonuclease RRP40 (EC 3.1.13.-)	protein	175	25% helix, 26% strand	Q08285

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.29	0.75	15	empty

Compared structures

2JA9 · Structure of the N-terminal deletion of yeast exosome component Rrp40 · the same entry in another collection · chain A against A, TM-score 1.00
Q08285 · AlphaFold monomer V2.0 prediction for exosome complex component RRP40 (Q08285) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q08285
Elsewhere: RCSB PDB 2JA9 · PDBe 2JA9 · UniProt Q08285

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