MolNFT v1 · #40843 · protein

NMR analysis of mouse cripto cfc domain

2J5H · Teratocarcinoma-derived growth factor: “NMR analysis of mouse cripto cfc domain”. Solution nmr, 2 ligands (ACE, NH2). MolNFT v1 #40843 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2J5H
Type: protein
Length: 39 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Teratocarcinoma-derived growth factor
UniProt: P51865
Ligands: ACE, NH2

Structure

solution nmr · 1 distinct chain · 0% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Teratocarcinoma-derived growth factor	protein	39	0% helix, 0% strand	P51865

Ligands and binding sites

ACE · Acetyl group · ligand · chains A
NH2 · Amino group · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 3 disulfide, 1 covalent (disulfide, covalent ligand).

Compared structures

2J5H · NMR analysis of mouse CRIPTO CFC domain · the same entry in another collection · chain A against A, TM-score 1.00
P51865 · AlphaFold monomer V2.0 prediction for teratocarcinoma-derived growth factor (P51865) · a predicted model of the same protein · chain A against A, TM-score 0.31

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P51865
Elsewhere: RCSB PDB 2J5H · PDBe 2J5H · UniProt P51865

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