MolNFT v1 · #40619 · protein
Crystal structure of the N-terminal dimer domain of E.COLI dsbg
2IY2 · Thiol disulfide interchange protein dsbg: “Crystal structure of the N-terminal dimer domain of E.COLI dsbg”. X-ray diffraction, 1 ligand (CD), 1 pocket (best druggability 0.31). MolNFT v1 #40619 on GenesisL1: 3D structure, binding…
- PDB
- 2IY2
- Type
- protein
- Length
- 136 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Thiol disulfide interchange protein dsbg
- UniProt
- P77202
- Ligands
- CD
- Pockets
- 1 · best druggability 0.31
Structure
x-ray diffraction · 2 distinct chains · 24% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Thiol disulfide interchange protein dsbg | protein | 69 | 22% helix, 42% strand | P77202 |
| B | Thiol disulfide interchange protein dsbg | protein | 67 | 27% helix, 40% strand | P77202 |
Ligands and binding sites
- CD · Cadmium ion · metal · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 84 | 0.31 | 0.73 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 932 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 2IY2 · Crystal structure of the N-terminal dimer domain of E.coli DsbG · the same entry in another collection · chain A against A, TM-score 1.00
- P77202 · AlphaFold monomer V2.0 prediction for THIOL:DISULFIDE interchange protein dsbg (P77202) · a predicted model of the same protein · chain B against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P77202
- Elsewhere: RCSB PDB 2IY2 · PDBe 2IY2 · UniProt P77202
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