MolNFT v1 · #40487 · protein
Regulation of the dha operon of lactococcus lactis
2IU6 · Dihydroxyacetone kinase: “Regulation of the dha operon of lactococcus lactis”. X-ray diffraction, 3 pockets (best druggability 0.85). MolNFT v1 #40487 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2IU6
- Type
- protein
- Length
- 638 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dihydroxyacetone kinase
- EC
- 2.7.1.2
- UniProt
- Q9CIW0
- Pockets
- 3 · best druggability 0.85
Structure
x-ray diffraction · 2 distinct chains · 35% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dihydroxyacetone kinase (EC 2.7.1.2) | protein | 317 | 35% helix, 25% strand | Q9CIW0 |
| B | Dihydroxyacetone kinase (EC 2.7.1.2) | protein | 321 | 35% helix, 26% strand | Q9CIW0 |
Ligands and binding sites
- GOL · Glycerol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 641 | 0.85 | 0.89 | 95 | empty |
| 2 | 99 | 0.51 | 0.82 | 29 | empty |
| 3 | 50 | 0.51 | 0.88 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 2285 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9CIW0
- Elsewhere: RCSB PDB 2IU6 · PDBe 2IU6 · UniProt Q9CIW0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.