MolNFT v1 · #40400 · protein
Crystal structure of fructose-bisphosphate aldolase, class I from porphyromonas gingivalis
2IQT · Fructose-bisphosphate aldolase class 1: “Crystal structure of fructose-bisphosphate aldolase, class I from porphyromonas gingivalis”. X-ray diffraction, 1 pocket (best druggability 0.58). MolNFT v1 #40400 on GenesisL1: 3D structure…
- PDB
- 2IQT
- Type
- protein
- Length
- 295 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fructose-bisphosphate aldolase class 1
- EC
- 4.1.2.13
- UniProt
- P60053
- Pockets
- 1 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 48% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fructose-bisphosphate aldolase class 1 (EC 4.1.2.13) | protein | 295 | 48% helix, 20% strand | P60053 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 232 | 0.58 | 0.80 | 27 | empty |
Modifications
Observed in the structure: 14 modified (engineered).
Compared structures
- 2IQT · Crystal Structure of Fructose-Bisphosphate Aldolase, Class I from Porphyromonas gingivalis · the same entry in another collection · chain A against A, TM-score 1.00
- P60053 · AlphaFold monomer V2.0 prediction for fructose-bisphosphate aldolase class 1 (P60053) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P60053
- Elsewhere: RCSB PDB 2IQT · PDBe 2IQT · UniProt P60053
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