MolNFT v1 · #40064 · protein
New crystal form of transcriptional regulator TM1030 from thermotoga maritima
2IEK · Transcriptional regulator, tetr family: “New crystal form of transcriptional regulator TM1030 from thermotoga maritima”. X-ray diffraction, 1 pocket (best druggability 0.80). MolNFT v1 #40064 on GenesisL1: 3D structure, binding…
- PDB
- 2IEK
- Type
- protein
- Length
- 199 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional regulator, tetr family
- UniProt
- Q9X0C0
- Pockets
- 1 · best druggability 0.80
Structure
x-ray diffraction · 1 distinct chain · 81% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional regulator, tetr family | protein | 199 | 81% helix, 1% strand | Q9X0C0 |
Ligands and binding sites
- P6G · Hexaethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 615 | 0.80 | 0.85 | 45 | P6G |
Modifications
Observed in the structure: 7 modified (engineered).
Compared structures
- 2IEK · New crystal form of transcriptional regulator tm1030 from Thermotoga maritima · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X0C0
- Elsewhere: RCSB PDB 2IEK · PDBe 2IEK · UniProt Q9X0C0
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