MolNFT v1 · #39801 · protein
Crystal structure of a putative cellobiose-phosphate cleavage protein (EF3048) from enterococcus faecalis V583 at 1.70 a resolution
2I5I · UPF0249 protein EF_3048: “Crystal structure of a putative cellobiose-phosphate cleavage protein (EF3048) from enterococcus faecalis…”. X-ray diffraction, 4 pockets (best druggability 0.68). MolNFT v1 #39801 on GenesisL1: 3D…
- PDB
- 2I5I
- Type
- protein
- Length
- 522 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- UPF0249 protein EF_3048
- UniProt
- P59745
- Pockets
- 4 · best druggability 0.68
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | UPF0249 protein EF_3048 | protein | 261 | 46% helix, 15% strand | P59745 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 240 | 0.68 | 0.85 | 33 | empty |
| 2 | 161 | 0.49 | 0.78 | 25 | empty |
| 3 | 153 | 0.46 | 0.77 | 31 | empty |
| 4 | 52 | 0.32 | 0.77 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 773 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 14 modified (engineered).
Compared structures
- 2I5I · Crystal structure of a putative cellobiose-phosphate cleavage protein (EF3048) from… · the same entry in another collection · chain A against A, TM-score 1.00
- P59745 · AlphaFold monomer V2.0 prediction for carbohydrate deacetylase (P59745) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P59745
- Elsewhere: RCSB PDB 2I5I · PDBe 2I5I · UniProt P59745
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