MolNFT v1 · #39564 · protein
Crystal structure of L-fuconate dehydratase from xanthomonas campestris liganded with mg++ and D-erythronohydroxamate
2HXT: “Crystal structure of L-fuconate dehydratase from xanthomonas campestris liganded with mg++ and…”. X-ray diffraction, 2 ligands (EHM, MG), 3 pockets (best druggability 0.60). MolNFT v1 #39564 on GenesisL1: 3D structure, binding sites…
- PDB
- 2HXT
- Type
- protein
- Length
- 434 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- L-fuconate dehydratase
- UniProt
- Q8P3K2
- Ligands
- EHM, MG
- Pockets
- 3 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 47% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | L-fuconate dehydratase | protein | 434 | 47% helix, 16% strand | Q8P3K2 |
Ligands and binding sites
- EHM · (2R,3R)-N,2,3,4-tetrahydroxybutanamide · ligand · chains A
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 150 | 0.60 | 0.84 | 34 | EHM |
| 2 | 92 | 0.39 | 0.77 | 20 | empty |
| 3 | 51 | 0.26 | 0.74 | 19 | empty |
Compared structures
- 2HXT · Crystal structure of L-Fuconate Dehydratase from Xanthomonas campestris liganded with… · the same entry in another collection · chain A against A, TM-score 1.00
- Q8P3K2 · AlphaFold monomer V2.0 prediction for L-fuconate dehydratase (Q8P3K2) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8P3K2
- Elsewhere: RCSB PDB 2HXT · PDBe 2HXT · UniProt Q8P3K2
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