MolNFT v1 · #39114 · protein
Crystal structure of the bc domain of ACC2
2HJW · Acetyl-CoA carboxylase 2: “Crystal structure of the bc domain of ACC2”. X-ray diffraction, 4 pockets (best druggability 0.70). MolNFT v1 #39114 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2HJW
- Type
- protein
- Length
- 494 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Acetyl-CoA carboxylase 2
- EC
- 6.4.1.2
- UniProt
- Q6KE87
- Pockets
- 4 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Acetyl-CoA carboxylase 2 (EC 6.4.1.2) | protein | 494 | 35% helix, 21% strand | Q6KE87 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 928 | 0.70 | 0.75 | 79 | empty |
| 2 | 350 | 0.62 | 0.78 | 45 | empty |
| 3 | 175 | 0.50 | 0.77 | 25 | empty |
| 4 | 88 | 0.41 | 0.78 | 19 | empty |
Compared structures
- 2HJW · Crystal Structure of the BC domain of ACC2 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6KE87
- Elsewhere: RCSB PDB 2HJW · PDBe 2HJW · UniProt Q6KE87
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