MolNFT v1 · #39020 · protein
Structure of S65A Y66F E222A GFP variant after cyclization and carbon- carbon bond cleavage
2HGY · Green fluorescent protein: “Structure of S65A Y66F E222A GFP variant after cyclization and carbon- carbon bond cleavage”. X-ray diffraction, 1 ligand (CLV), 2 pockets (best druggability 0.79). MolNFT v1 #39020 on GenesisL1: 3D…
- PDB
- 2HGY
- Type
- protein
- Length
- 225 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Green fluorescent protein
- UniProt
- P42212
- Ligands
- CLV
- Pockets
- 2 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 9% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Green fluorescent protein | protein | 225 | 9% helix, 52% strand | P42212 |
Ligands and binding sites
- CLV · {(2S)-2-[(1S)-1-aminoethyl]-5-oxo-2,5-dihydro-1H-imidazol-1-yl}acetic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 111 | 0.79 | 0.98 | 25 | CLV |
| 2 | 52 | 0.39 | 0.81 | 14 | empty |
Modifications
Observed in the structure: 2 covalent (covalent ligand).
Compared structures
- 2HGY · Structure of S65A Y66F E222A GFP variant after cyclization and carbon-carbon bond cleavage · the same entry in another collection · chain A against A, TM-score 1.00
- P42212 · AlphaFold monomer V2.0 prediction for green fluorescent protein (P42212) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P42212
- Elsewhere: RCSB PDB 2HGY · PDBe 2HGY · UniProt P42212
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