MolNFT v1 · #38980 · protein

The NMR structures of a winged helix protein: genesis, 20 structures

2HFH: “The NMR structures of a winged helix protein: genesis, 20 structures”. Solution nmr, 1 pocket (best druggability 0.31). MolNFT v1 #38980 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2HFH
Type: protein
Length: 93 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Genesis
UniProt: Q63245
Pockets: 1 · best druggability 0.31

Structure

solution nmr · 1 distinct chain · 44% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Genesis	protein	93	44% helix, 4% strand	Q63245

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.31	0.76	12	empty

Compared structures

2HFH · The NMR structures of a winged helix protein: genesis, 20 structures · the same entry in another collection · chain A against A, TM-score 1.00
Q63245 · AlphaFold monomer V2.0 prediction for forkhead box protein D3 (Q63245) · a predicted model of the same protein · chain A against A, TM-score 0.65

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q63245
Elsewhere: RCSB PDB 2HFH · PDBe 2HFH · UniProt Q63245

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