MolNFT v1 · #38938 · protein
Structure of the peptidylprolyl isomerase domain of the human nk- tumour recognition protein
2HE9 · Nk-tumor recognition protein: “Structure of the peptidylprolyl isomerase domain of the human nk- tumour recognition protein”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.29). MolNFT v1 #38938 on GenesisL1: 3D…
- PDB
- 2HE9
- Type
- protein
- Length
- 344 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nk-tumor recognition protein
- EC
- 5.2.1.8
- UniProt
- P30414
- Ligands
- SO4
- Pockets
- 1 · best druggability 0.29
Structure
x-ray diffraction · 1 distinct chain · 13% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Nk-tumor recognition protein (EC 5.2.1.8) | protein | 172 | 13% helix, 33% strand | P30414 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 57 | 0.29 | 0.74 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 564 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 2HE9 · Structure of the peptidylprolyl isomerase domain of the human NK-tumour recognition… · the same entry in another collection · chain A against A, TM-score 1.00
- P30414 · AlphaFold monomer V2.0 prediction for nk-tumor recognition protein (P30414) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P30414
- Elsewhere: RCSB PDB 2HE9 · PDBe 2HE9 · UniProt P30414
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