MolNFT v1 · #38936 · protein

Ferm domain of EPB41L3 (dal-1)

2HE7 · Band 4.1-like protein 3: “Ferm domain of EPB41L3 (dal-1)”. X-ray diffraction, 3 pockets (best druggability 0.68). MolNFT v1 #38936 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2HE7
Type: protein
Length: 283 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Band 4.1-like protein 3
UniProt: Q9Y2J2
Pockets: 3 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 35% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Band 4.1-like protein 3	protein	283	35% helix, 26% strand	Q9Y2J2

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	513	0.68	0.79	54	empty
2	107	0.43	0.78	19	empty
3	53	0.29	0.75	14	empty

Compared structures

2HE7 · FERM domain of EPB41L3 (DAL-1) · the same entry in another collection · chain A against A, TM-score 1.00
Q9Y2J2 · AlphaFold monomer V2.0 prediction for band 4.1-like protein 3 (Q9Y2J2) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y2J2
Elsewhere: RCSB PDB 2HE7 · PDBe 2HE7 · UniProt Q9Y2J2

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.