MolNFT v1 · #38928 · protein
Crystal structure of hypothetical protein PA2218 from pseudomonas aeruginosa
2HDW: “Crystal structure of hypothetical protein PA2218 from pseudomonas aeruginosa”. X-ray diffraction, 7 pockets (best druggability 0.65). MolNFT v1 #38928 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2HDW
- Type
- protein
- Length
- 639 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hypothetical protein PA2218
- UniProt
- Q01609
- Pockets
- 7 · best druggability 0.65
Structure
x-ray diffraction · 2 distinct chains · 35% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hypothetical protein PA2218 | protein | 321 | 35% helix, 19% strand | Q01609 |
| B | Hypothetical protein PA2218 | protein | 318 | 35% helix, 19% strand | Q01609 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 414 | 0.65 | 0.78 | 36 | empty |
| 2 | 392 | 0.64 | 0.78 | 35 | empty |
| 3 | 156 | 0.57 | 0.82 | 23 | empty |
| 4 | 119 | 0.54 | 0.82 | 21 | empty |
| 5 | 96 | 0.39 | 0.76 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 2257 Ų buried · 38 hydrogen bonds · protein-protein
Compared structures
- 2HDW · Crystal structure of hypothetical protein PA2218 from Pseudomonas Aeruginosa · the same entry in another collection · chain A against A, TM-score 1.00
- Q01609 · AlphaFold monomer V2.0 prediction for uncharacterized protein PA2218 (Q01609) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q01609
- Elsewhere: RCSB PDB 2HDW · PDBe 2HDW · UniProt Q01609
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