MolNFT v1 · #38886 · protein
Structure of S65T Y66F GFP variant after cyclization, carbon-carbon bond cleavage, and oxygen incorporation reactions
2HCG · Green fluorescent protein: “Structure of S65T Y66F GFP variant after cyclization, carbon-carbon bond cleavage, and oxygen incorporation…”. X-ray diffraction, 2 ligands (C99, MG), 1 pocket (best druggability 0.73). MolNFT v1 #38886…
- PDB
- 2HCG
- Type
- protein
- Length
- 233 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Green fluorescent protein
- UniProt
- P42212
- Ligands
- C99, MG
- Pockets
- 1 · best druggability 0.73
Structure
x-ray diffraction · 1 distinct chain · 14% helix, 50% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Green fluorescent protein | protein | 233 | 14% helix, 50% strand | P42212 |
Ligands and binding sites
- C99 · {(2R)-2-[(1S,2R)-1-amino-2-hydroxypropyl]-2-hydroxy-4, 5-dioxoimidazolidin-1-yl}acetic acid · ligand · chains A
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 61 | 0.73 | 0.98 | 22 | C99 |
Modifications
Observed in the structure: 2 covalent (covalent ligand).
Compared structures
- 2HCG · Structure of S65T Y66F GFP variant after cyclization, carbon-carbon bond cleavage, and… · the same entry in another collection · chain A against A, TM-score 1.00
- P42212 · AlphaFold monomer V2.0 prediction for green fluorescent protein (P42212) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P42212
- Elsewhere: RCSB PDB 2HCG · PDBe 2HCG · UniProt P42212
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