MolNFT v1 · #38729 · protein

Solution structure of the etafh domain from the human leukemia- associated fusion protein AML1-eto

2H7B · Core-binding factor, ML1-eto: “Solution structure of the etafh domain from the human leukemia- associated fusion protein AML1-eto”. Solution nmr, 1 pocket (best druggability 0.34). MolNFT v1 #38729 on GenesisL1: 3D structure…

PDB: 2H7B
Type: protein
Length: 105 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Core-binding factor, ML1-eto
UniProt: Q7Z4J5
Pockets: 1 · best druggability 0.34

Structure

solution nmr · 1 distinct chain · 64% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Core-binding factor, ML1-eto	protein	105	64% helix, 0% strand	Q7Z4J5

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	54	0.34	0.78	20	empty

Compared structures

2H7B · Solution structure of the eTAFH domain from the human leukemia-associated fusion protein… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7Z4J5
Elsewhere: RCSB PDB 2H7B · PDBe 2H7B · UniProt Q7Z4J5

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