MolNFT v1 · #38616 · protein

Trans-(4-AMINOMETHYL)PHENYLAZOBENZOIC acid-app bound to dpc micelles

2H3T · Pancreatic hormone: “Trans-(4-AMINOMETHYL)PHENYLAZOBENZOIC acid-app bound to dpc micelles”. Solution nmr, 2 ligands (EAB, NH2). MolNFT v1 #38616 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2H3T
Type: protein
Length: 33 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pancreatic hormone
UniProt: P68249
Ligands: EAB, NH2

Structure

solution nmr · 2 distinct chains · 45% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pancreatic hormone	protein	9	0% helix, 0% strand	P68249
B	Pancreatic hormone	protein	24	63% helix, 0% strand	P68249

Ligands and binding sites

EAB · (3-{(E)-[3-(aminomethyl)phenyl]diazenyl}phenyl)acetic acid · ligand · chains A, B
NH2 · Amino group · ion · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 33 Å² buried · 0 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 covalent (covalent ligand).

Compared structures

2H3T · trans-(4-aminomethyl)phenylazobenzoic acid-aPP bound to DPC micelles · the same entry in another collection · chain B against B, TM-score 1.00
P68249 · AlphaFold monomer V2.0 prediction for pancreatic hormone (P68249) · a predicted model of the same protein · chain B against A, TM-score 0.51

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P68249
Elsewhere: RCSB PDB 2H3T · PDBe 2H3T · UniProt P68249

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