MolNFT v1 · #38589 · protein
Crystal structure of SARS-cov main protease with authentic N and C-termini
2H2Z · Replicase polyprotein 1AB: “Crystal structure of SARS-cov main protease with authentic N and C-termini”. X-ray diffraction, 2 pockets (best druggability 0.43). MolNFT v1 #38589 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 2H2Z
- Type
- protein
- Length
- 306 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Replicase polyprotein 1AB
- EC
- 3.4.22.-
- UniProt
- P59641
- Pockets
- 2 · best druggability 0.43
Structure
x-ray diffraction · 1 distinct chain · 25% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Replicase polyprotein 1AB (EC 3.4.22.-) | protein | 306 | 25% helix, 29% strand | P59641 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 165 | 0.43 | 0.74 | 20 | empty |
| 2 | 116 | 0.40 | 0.75 | 25 | empty |
Compared structures
- 2H2Z · Crystal structure of SARS-CoV main protease with authentic N and C-termini · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P59641
- Elsewhere: RCSB PDB 2H2Z · PDBe 2H2Z · UniProt P59641
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