MolNFT v1 · #38313 · protein
Crystal structure of the wildtype mhv coronavirus non-structural protein NSP15
2GTH · Replicase polyprotein 1AB: “Crystal structure of the wildtype mhv coronavirus non-structural protein NSP15”. X-ray diffraction, 4 pockets (best druggability 0.60). MolNFT v1 #38313 on GenesisL1: 3D structure, binding sites and…
- PDB
- 2GTH
- Type
- protein
- Length
- 348 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Replicase polyprotein 1AB
- UniProt
- P16342
- Pockets
- 4 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 21% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Replicase polyprotein 1AB | protein | 348 | 21% helix, 29% strand | P16342 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 239 | 0.60 | 0.80 | 33 | empty |
| 2 | 180 | 0.50 | 0.77 | 30 | empty |
| 3 | 120 | 0.41 | 0.75 | 20 | empty |
| 4 | 74 | 0.29 | 0.72 | 14 | empty |
Compared structures
- 2GTH · crystal structure of the wildtype MHV coronavirus non-structural protein nsp15 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16342
- Elsewhere: RCSB PDB 2GTH · PDBe 2GTH · UniProt P16342
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