MolNFT v1 · #38308 · protein
Crystal structure of the hypthetical protein from bacillus cereus (atcc 14579). northeast structural genomics target BCR11
2GTC · UPF0145 protein BC_1816: “Crystal structure of the hypthetical protein from bacillus cereus (atcc 14579). northeast structural genomics…”. X-ray diffraction, 6 pockets (best druggability 0.82). MolNFT v1 #38308 on GenesisL1: 3D…
- PDB
- 2GTC
- Type
- protein
- Length
- 515 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- UPF0145 protein BC_1816
- UniProt
- Q81EZ2
- Pockets
- 6 · best druggability 0.82
Structure
x-ray diffraction · 1 distinct chain · 28% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E | UPF0145 protein BC_1816 | protein | 103 | 28% helix, 38% strand | Q81EZ2 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1059 | 0.82 | 0.84 | 81 | empty |
| 2 | 158 | 0.44 | 0.75 | 32 | empty |
| 3 | 73 | 0.42 | 0.80 | 19 | empty |
| 4 | 67 | 0.41 | 0.80 | 16 | empty |
| 5 | 64 | 0.39 | 0.80 | 18 | empty |
Interfaces
5 interfaces between chains.
- B–C · 1515 Ų buried · 27 hydrogen bonds · protein-protein
- B–E · 1493 Ų buried · 24 hydrogen bonds · protein-protein
- A–D · 1445 Ų buried · 22 hydrogen bonds · protein-protein
- D–E · 1398 Ų buried · 24 hydrogen bonds · protein-protein
- A–C · 1374 Ų buried · 21 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 30 modified (engineered).
Compared structures
- 2GTC · Crystal structure of the hypthetical protein from Bacillus cereus (ATCC 14579). Northeast… · the same entry in another collection · chain A against A, TM-score 1.00
- Q81EZ2 · AlphaFold monomer V2.0 prediction for UPF0145 protein BC_1816 (Q81EZ2) · a predicted model of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q81EZ2
- Elsewhere: RCSB PDB 2GTC · PDBe 2GTC · UniProt Q81EZ2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.