MolNFT v1 · #38260 · protein

Crystal structure of the human KIF2 motor domain in complex with ADP

2GRY · Kinesin-like protein KIF2: “Crystal structure of the human KIF2 motor domain in complex with ADP”. X-ray diffraction, 3 ligands (ADP, MG, UNX), 1 pocket (best druggability 0.49). MolNFT v1 #38260 on GenesisL1: 3D structure, binding…

PDB: 2GRY
Type: protein
Length: 327 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Kinesin-like protein KIF2
Ligands: ADP, MG, UNX
Pockets: 1 · best druggability 0.49

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Kinesin-like protein KIF2	protein	327	37% helix, 28% strand	—

Ligands and binding sites

ADP · Adenosine-5'-diphosphate · ligand · chains A
MG · Magnesium ion · metal · chains A
UNX · Unknown atom or ion · ion · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	117	0.49	0.80	22	empty

Compared structures

2GRY · Crystal structure of the human KIF2 motor domain in complex with ADP · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2GRY · PDBe 2GRY

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