MolNFT v1 · #38166 · protein

Bacteriophage HK97 prohead II crystal structure

2GP1 · Major capsid protein: “Bacteriophage HK97 prohead II crystal structure”. X-ray diffraction, 20 pockets (best druggability 0.82). MolNFT v1 #38166 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2GP1
Type: protein
Length: 1,778 residues
Chains: 7
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Major capsid protein
UniProt: P49861
Pockets: 20 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 28% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, E, F, G	Major capsid protein	protein	254	28% helix, 29% strand	P49861

Pockets

20 pockets found on a 1 Å grid, 15 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1128	0.82	0.83	129	empty
2	1038	0.81	0.82	109	empty
3	761	0.79	0.83	86	empty
4	607	0.76	0.82	61	empty
5	506	0.70	0.80	65	empty

Interfaces

12 interfaces between chains.

E–F · 1529 Å² buried · 15 hydrogen bonds · protein-protein
A–F · 1410 Å² buried · 11 hydrogen bonds · protein-protein
B–C · 1372 Å² buried · 16 hydrogen bonds · protein-protein
C–D · 1314 Å² buried · 13 hydrogen bonds · protein-protein
D–E · 1097 Å² buried · 14 hydrogen bonds · protein-protein

Compared structures

2GP1 · Bacteriophage HK97 Prohead II crystal structure · the same entry in another collection · chain E against E, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P49861
Elsewhere: RCSB PDB 2GP1 · PDBe 2GP1 · UniProt P49861

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