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MolNFT v1 · #37690 · protein

Complex of TM1A(1-14)ZIP with TM9A(251-284): a model for the polymerization domain ("overlap region") of tropomyosin, northeast structural genomics target OR9

2G9J · Tropomyosin 1 alpha chain: “Complex of TM1A(1-14)ZIP with TM9A(251-284): a model for the polymerization domain ("overlap region") of…”. Solution nmr. MolNFT v1 #37690 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
2G9J
Type
protein
Length
140 residues
Chains
4
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Tropomyosin 1 alpha chain; Tropomyosin 1 alpha CHAIN/GENERAL control protein GCN4
UniProt
Q63609, P03069

Structure

solution nmr · 2 distinct chains · 83% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
C, DTropomyosin 1 alpha chainprotein3776% helix, 0% strandQ63609
A, BTropomyosin 1 alpha CHAIN/GENERAL control protein GCN4protein3391% helix, 0% strandQ63609, P03069

Interfaces

6 interfaces between chains.

  • C–D · 683 Ų buried · 4 hydrogen bonds · protein-protein
  • A–B · 621 Ų buried · 7 hydrogen bonds · protein-protein
  • A–D · 322 Ų buried · 3 hydrogen bonds · protein-protein
  • C–B · 277 Ų buried · 2 hydrogen bonds · protein-protein
  • D–B · 254 Ų buried · 1 hydrogen bond · protein-protein

Compared structures

  • 2G9J · Complex of TM1a(1-14)Zip with TM9a(251-284): a model for the polymerization domain… · the same entry in another collection · chain C against C, TM-score 1.00
  • P03069 · AlphaFold monomer V2.0 prediction for general control transcription factor GCN4 (P03069) · a predicted model of the same protein · chain B against A, TM-score 0.78

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