MolNFT v1 · #37605 · protein
The crystal structure of ribd from escherichia COLI
2G6V · Riboflavin biosynthesis protein ribd: “The crystal structure of ribd from escherichia COLI”. X-ray diffraction, 9 pockets (best druggability 0.71). MolNFT v1 #37605 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2G6V
- Type
- protein
- Length
- 718 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Riboflavin biosynthesis protein ribd
- EC
- 1.1.1.193, 3.5.4.26
- UniProt
- P25539
- Pockets
- 9 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 30% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Riboflavin biosynthesis protein ribd (EC 1.1.1.193, 3.5.4.26) | protein | 355 | 31% helix, 23% strand | P25539 |
| B | Riboflavin biosynthesis protein ribd (EC 1.1.1.193, 3.5.4.26) | protein | 363 | 29% helix, 22% strand | P25539 |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 72 | 0.71 | 0.96 | 26 | empty |
| 2 | 310 | 0.65 | 0.81 | 33 | empty |
| 3 | 275 | 0.65 | 0.82 | 32 | empty |
| 4 | 184 | 0.59 | 0.82 | 35 | empty |
| 5 | 196 | 0.55 | 0.79 | 25 | empty |
Interfaces
1 interface between chains.
- A–B · 1316 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 18 modified (engineered).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P25539
- Elsewhere: RCSB PDB 2G6V · PDBe 2G6V · UniProt P25539
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.