MolNFT v1 · #3751 · DNA
Binding of the antitumor drug nogalamycin and its derivatives to DNA: structural comparison
1D22 · DNA (5'-D(*(5CM)P*GP*TP*(AS)P*(5CM)P*G)-3'): “Binding of the antitumor drug nogalamycin and its derivatives to DNA: structural comparison”. X-ray diffraction, 1 ligand (NGU). MolNFT v1 #3751 on GenesisL1: 3D structure, binding sites…
- PDB
- 1D22
- Type
- DNA
- Length
- 12 nucleotides
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA (5'-D(*(5CM)P*GP*TP*(AS)P*(5CM)P*G)-3')
- Ligands
- NGU
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | DNA (5'-D(*(5CM)P*GP*TP*(AS)P*(5CM)P*G)-3') | dna | 6 | — | — |
Ligands and binding sites
- NGU · U-58872, hydroxy derivative of nogalamycin · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 299 Ų buried · 28 hydrogen bonds · nucleic-nucleic
Modifications
Observed in the structure: 6 modified (nucleotide modification).
Compared structures
- 1D22 · Binding of the antitumor drug nogalamycin and its derivatives to DNA: structural… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1D22 · PDBe 1D22
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