MolNFT v1 · #37353 · protein

Crystal structure of rat carnitine palmitoyltransferase 2 in space group P43212

2FYO · Carnitine O-palmitoyltransferase II, mitochondrial: “Crystal structure of rat carnitine palmitoyltransferase 2 in space group P43212”. X-ray diffraction, 5 pockets (best druggability 0.81). MolNFT v1 #37353 on GenesisL1: 3D…

PDB: 2FYO
Type: protein
Length: 625 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Carnitine O-palmitoyltransferase II, mitochondrial
EC: 2.3.1.21
UniProt: P18886
Pockets: 5 · best druggability 0.81

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Carnitine O-palmitoyltransferase II, mitochondrial (EC 2.3.1.21)	protein	625	47% helix, 15% strand	P18886

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1021	0.81	0.82	92	empty
2	60	0.49	0.86	20	empty
3	59	0.35	0.77	13	empty
4	75	0.34	0.76	19	empty
5	60	0.33	0.76	14	empty

Modifications

Observed in the structure: 12 modified (engineered).

Compared structures

2FYO · Crystal structure of rat carnitine palmitoyltransferase 2 in space group P43212 · the same entry in another collection · chain A against A, TM-score 1.00
P18886 · AlphaFold monomer V2.0 prediction for carnitine O-palmitoyltransferase 2, mitochondrial… · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P18886
Elsewhere: RCSB PDB 2FYO · PDBe 2FYO · UniProt P18886

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