MolNFT v1 · #37281 · protein

Structure of pure (N5-carboxyaminoimidazole ribonucleotide mutase) H89N from the acidophilic bacterium acetobacter aceti, at pH 7

2FWA: “Structure of pure (N5-carboxyaminoimidazole ribonucleotide mutase) H89N from the acidophilic bacterium…”. X-ray diffraction, 2 pockets (best druggability 0.31). MolNFT v1 #37281 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 2FWA
Type: protein
Length: 320 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: N5-carboxyaminoimidazole ribonucleotide mutase
UniProt: Q2QJL3
Pockets: 2 · best druggability 0.31

Structure

x-ray diffraction · 2 distinct chains · 47% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	N5-carboxyaminoimidazole ribonucleotide mutase	protein	159	47% helix, 16% strand	Q2QJL3
B	N5-carboxyaminoimidazole ribonucleotide mutase	protein	161	47% helix, 16% strand	Q2QJL3

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	51	0.31	0.76	12	empty
2	56	0.29	0.75	15	empty

Interfaces

1 interface between chains.

A–B · 1647 Å² buried · 28 hydrogen bonds · protein-protein

Compared structures

2FWA · Structure of PurE (N5-carboxyaminoimidazole ribonucleotide mutase) H89N from the… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q2QJL3
Elsewhere: RCSB PDB 2FWA · PDBe 2FWA · UniProt Q2QJL3

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