MolNFT v1 · #36994 · protein

Crystal structure of a tat-interacting protein homologue (HTATIP2, AW111545, CC3, TIP30) from mus musculus at 2.30 a resolution

2FMU · HIV-1 tat interactive protein 2, 30 kda homolog: “Crystal structure of a tat-interacting protein homologue (HTATIP2, AW111545, CC3, TIP30) from mus musculus at…”. X-ray diffraction, 3 pockets (best druggability 0.51). MolNFT v1…

PDB: 2FMU
Type: protein
Length: 209 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: HIV-1 tat interactive protein 2, 30 kda homolog
Pockets: 3 · best druggability 0.51

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	HIV-1 tat interactive protein 2, 30 kda homolog	protein	209	45% helix, 20% strand	—

Ligands and binding sites

EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	116	0.51	0.81	21	empty
2	68	0.38	0.79	18	empty
3	104	0.36	0.74	19	empty

Compared structures

2FMU · Crystal structure of a tat-interacting protein homologue (htatip2, aw111545, cc3, tip30)… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2FMU · PDBe 2FMU

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