MolNFT v1 · #36885 · protein
Crystal structure of the C-terminal domain of the exocyst subunit SEC6P
2FJI · Exocyst complex component SEC6: “Crystal structure of the C-terminal domain of the exocyst subunit SEC6P”. X-ray diffraction, 2 pockets (best druggability 0.33). MolNFT v1 #36885 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 2FJI
- Type
- protein
- Length
- 795 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Exocyst complex component SEC6
- UniProt
- P32844
- Pockets
- 2 · best druggability 0.33
Structure
x-ray diffraction · 2 distinct chains · 73% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| 1 | Exocyst complex component SEC6 | protein | 399 | 74% helix, 1% strand | P32844 |
| 2 | Exocyst complex component SEC6 | protein | 396 | 72% helix, 1% strand | P32844 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 60 | 0.33 | 0.77 | 14 | empty |
| 2 | 50 | 0.26 | 0.74 | 12 | empty |
Compared structures
- 2FJI · Crystal structure of the C-terminal domain of the exocyst subunit Sec6p · the same entry in another collection · chain 1 against 1, TM-score 1.00
- P32844 · AlphaFold monomer V2.0 prediction for exocyst complex component SEC6 (P32844) · a predicted model of the same protein · chain 1 against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P32844
- Elsewhere: RCSB PDB 2FJI · PDBe 2FJI · UniProt P32844
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