MolNFT v1 · #36832 · protein

Solution structure of human relaxin-3

2FHW · Relaxin 3 (prorelaxin H3) (insulin-like peptide INSL7)…: “Solution structure of human relaxin-3”. Solution nmr. MolNFT v1 #36832 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2FHW
Type: protein
Length: 51 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Relaxin 3 (prorelaxin H3) (insulin-like peptide INSL7) (insulin-like peptide 7)
UniProt: Q8WXF3

Structure

solution nmr · 2 distinct chains · 53% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	Relaxin 3 (prorelaxin H3) (insulin-like peptide INSL7) (insulin-like peptide 7)	protein	27	41% helix, 7% strand	Q8WXF3
A	Relaxin 3 (prorelaxin H3) (insulin-like peptide INSL7) (insulin-like peptide 7)	protein	24	67% helix, 8% strand	Q8WXF3

Interfaces

1 interface between chains.

B–A · 587 Å² buried · 15 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

2FHW · Solution structure of human relaxin-3 · the same entry in another collection · chain B against B, TM-score 1.00
Q8WXF3 · AlphaFold monomer V2.0 prediction for relaxin-3 (Q8WXF3) · a predicted model of the same protein · chain A against A, TM-score 0.73

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8WXF3
Elsewhere: RCSB PDB 2FHW · PDBe 2FHW · UniProt Q8WXF3

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