MolNFT v1 · #36828 · protein
Crystal structure of general stress protein from bacteroides thetaiotaomicron
2FHQ · Putative general stress protein: “Crystal structure of general stress protein from bacteroides thetaiotaomicron”. X-ray diffraction, 3 pockets (best druggability 0.66). MolNFT v1 #36828 on GenesisL1: 3D structure, binding sites and…
- PDB
- 2FHQ
- Type
- protein
- Length
- 269 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative general stress protein
- Pockets
- 3 · best druggability 0.66
Structure
x-ray diffraction · 2 distinct chains · 23% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative general stress protein | protein | 135 | 21% helix, 48% strand | — |
| B | Putative general stress protein | protein | 134 | 25% helix, 49% strand | — |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 326 | 0.66 | 0.81 | 41 | empty |
| 2 | 287 | 0.58 | 0.77 | 30 | empty |
| 3 | 93 | 0.48 | 0.81 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1161 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 2FHQ · Crystal Structure of General Stress Protein from Bacteroides thetaiotaomicron · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2FHQ · PDBe 2FHQ
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