MolNFT v1 · #36811 · protein
Structure and dimerization of the kinase domain from yeast SNF1
2FH9 · SNF1 kinase: “Structure and dimerization of the kinase domain from yeast SNF1”. X-ray diffraction, 2 pockets (best druggability 0.72). MolNFT v1 #36811 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2FH9
- Type
- protein
- Length
- 255 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SNF1 kinase
- EC
- 2.7.1.-
- UniProt
- P06782
- Pockets
- 2 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SNF1 kinase (EC 2.7.1.-) | protein | 255 | 36% helix, 16% strand | P06782 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 610 | 0.72 | 0.79 | 53 | empty |
| 2 | 63 | 0.27 | 0.73 | 13 | empty |
Compared structures
- 2FH9 · Structure and dimerization of the kinase domain from yeast Snf1 · the same entry in another collection · chain A against A, TM-score 1.00
- P06782 · AlphaFold monomer V2.0 prediction for carbon catabolite-derepressing protein kinase… · a predicted model of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06782
- Elsewhere: RCSB PDB 2FH9 · PDBe 2FH9 · UniProt P06782
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