MolNFT v1 · #36517 · protein

Crystal structure of an orotidine-5'-monophosphate decarboxylase homolog from P.FALCIPARUM

2F84 · Orotidine monophosphate decarboxylase: “Crystal structure of an orotidine-5'-monophosphate decarboxylase homolog from P.FALCIPARUM”. X-ray diffraction, 1 ligand (PO4), 4 pockets (best druggability 0.46). MolNFT v1 #36517 on…

PDB: 2F84
Type: protein
Length: 323 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Orotidine monophosphate decarboxylase
EC: 4.1.1.23
UniProt: Q8IJH3
Ligands: PO4
Pockets: 4 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 56% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Orotidine monophosphate decarboxylase (EC 4.1.1.23)	protein	323	56% helix, 14% strand	Q8IJH3

Ligands and binding sites

PO4 · Phosphate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	129	0.46	0.78	22	empty
2	85	0.41	0.78	19	empty
3	99	0.40	0.77	14	empty
4	95	0.36	0.75	25	PO4

Compared structures

2F84 · Crystal Structure of an orotidine-5'-monophosphate decarboxylase homolog from P.falciparum · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8IJH3
Elsewhere: RCSB PDB 2F84 · PDBe 2F84 · UniProt Q8IJH3

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