MolNFT v1 · #36211 · protein
The crystal structure of the C-terminal domain of aquifex aeolicus pilt
2EYU · Twitching motility protein pilt: “The crystal structure of the C-terminal domain of aquifex aeolicus pilt”. X-ray diffraction, 1 ligand (SO4), 3 pockets (best druggability 0.57). MolNFT v1 #36211 on GenesisL1: 3D structure, binding…
- PDB
- 2EYU
- Type
- protein
- Length
- 494 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Twitching motility protein pilt
- Ligands
- SO4
- Pockets
- 3 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 47% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Twitching motility protein pilt | protein | 247 | 47% helix, 20% strand | — |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 401 | 0.57 | 0.74 | 38 | empty |
| 2 | 285 | 0.51 | 0.74 | 34 | SO4 |
| 3 | 61 | 0.30 | 0.75 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 204 Ų buried · 2 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 16 modified (engineered).
Compared structures
- 2EYU · The Crystal Structure of the C-terminal Domain of Aquifex aeolicus PilT · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2EYU · PDBe 2EYU
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