MolNFT v1 · #35766 · protein

Solution structure of the human STAP2 SH2 domain

2EL8 · Signal-transducing adaptor protein 2: “Solution structure of the human STAP2 SH2 domain”. Solution nmr, 1 pocket (best druggability 0.30). MolNFT v1 #35766 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2EL8
Type: protein
Length: 118 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Signal-transducing adaptor protein 2
UniProt: Q9UGK3
Pockets: 1 · best druggability 0.30

Structure

solution nmr · 1 distinct chain · 18% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Signal-transducing adaptor protein 2	protein	118	18% helix, 17% strand	Q9UGK3

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	56	0.30	0.75	12	empty

Compared structures

2EL8 · Solution structure of the human STAP2 SH2 domain · the same entry in another collection · chain A against A, TM-score 1.00
Q9UGK3 · AlphaFold monomer V2.0 prediction for signal-transducing adaptor protein 2 (Q9UGK3) · a predicted model of the same protein · chain A against A, TM-score 0.75

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UGK3
Elsewhere: RCSB PDB 2EL8 · PDBe 2EL8 · UniProt Q9UGK3

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