MolNFT v1 · #35747 · protein

Structure of ST1219 protein from sulfolobus tokodaii

2EKM · Hypothetical protein ST1511: “Structure of ST1219 protein from sulfolobus tokodaii”. X-ray diffraction, 4 pockets (best druggability 0.74). MolNFT v1 #35747 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2EKM
Type: protein
Length: 480 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hypothetical protein ST1511
UniProt: Q970U0
Pockets: 4 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Hypothetical protein ST1511	protein	160	29% helix, 36% strand	Q970U0

Ligands and binding sites

GOL · Glycerol · additive · 2 copies · chains A, B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	129	0.74	0.93	20	empty
2	241	0.55	0.77	25	GOL
3	187	0.50	0.76	25	GOL
4	156	0.48	0.77	20	empty

Interfaces

3 interfaces between chains.

A–B · 2006 Å² buried · 32 hydrogen bonds · protein-protein
A–C · 1984 Å² buried · 34 hydrogen bonds · protein-protein
B–C · 1958 Å² buried · 31 hydrogen bonds · protein-protein

Compared structures

2EKM · Structure of ST1219 protein from Sulfolobus tokodaii · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q970U0
Elsewhere: RCSB PDB 2EKM · PDBe 2EKM · UniProt Q970U0

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