MolNFT v1 · #35644 · protein

Crystal structure of hyperthermophilic archaeal RNase hi

2EHG · Ribonuclease hi: “Crystal structure of hyperthermophilic archaeal RNase hi”. X-ray diffraction, 1 pocket (best druggability 0.28). MolNFT v1 #35644 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2EHG
Type: protein
Length: 149 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ribonuclease hi
EC: 3.1.26.4
UniProt: Q973Z8
Pockets: 1 · best druggability 0.28

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ribonuclease hi (EC 3.1.26.4)	protein	149	40% helix, 26% strand	Q973Z8

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.28	0.75	17	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

2EHG · Crystal structure of hyperthermophilic archaeal RNase HI · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q973Z8
Elsewhere: RCSB PDB 2EHG · PDBe 2EHG · UniProt Q973Z8

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