MolNFT v1 · #35492 · protein

Solution structure of rsgi ruh-069, a GTF2I domain in human cdna

2ED2 · General transcription factor II-I: “Solution structure of rsgi ruh-069, a GTF2I domain in human cdna”. Solution nmr, 1 pocket (best druggability 0.26). MolNFT v1 #35492 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2ED2
Type: protein
Length: 99 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: General transcription factor II-I
UniProt: P78347
Pockets: 1 · best druggability 0.26

Structure

solution nmr · 1 distinct chain · 36% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	General transcription factor II-I	protein	99	36% helix, 8% strand	P78347

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.26	0.73	15	empty

Compared structures

2ED2 · Solution Structure of RSGI RUH-069, a GTF2I domain in human cDNA · the same entry in another collection · chain A against A, TM-score 1.00
P78347 · AlphaFold monomer V2.0 prediction for general transcription factor II-I (P78347) · a predicted model of the same protein · chain A against A, TM-score 0.83

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P78347
Elsewhere: RCSB PDB 2ED2 · PDBe 2ED2 · UniProt P78347

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