MolNFT v1 · #35325 · protein
Acetylene hydratase from pelobacter acetylenicus
2E7Z · Acetylene hydratase ahy: “Acetylene hydratase from pelobacter acetylenicus”. X-ray diffraction, 4 ligands (MGD, SF4, NA), 5 pockets (best druggability 0.89). MolNFT v1 #35325 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2E7Z
- Type
- protein
- Length
- 727 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Acetylene hydratase ahy
- EC
- 4.2.1.71
- UniProt
- Q71EW5
- Ligands
- MGD, SF4, NA, W
- Pockets
- 5 · best druggability 0.89
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Acetylene hydratase ahy (EC 4.2.1.71) | protein | 727 | 37% helix, 17% strand | Q71EW5 |
Ligands and binding sites
- MGD · 2-amino-5,6-dimercapto-7-methyl-3,7,8A,9-tetrahydro-8-oxa-1,3,9,10-tetraaza-anthracen-4-one guanosine dinucleotide · ligand · 2 copies · chains A
- SF4 · Iron/sulfur cluster · ligand · chains A
- NA · Sodium ion · metal · chains A
- W · Tungsten ion · metal · chains A
- MPD · (4S)-2-methyl-2,4-pentanediol · additive · 2 copies · chains A
- ACT · Acetate ion · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 591 | 0.89 | 0.94 | 96 | MGD, W |
| 2 | 430 | 0.77 | 0.85 | 39 | MPD |
| 3 | 122 | 0.41 | 0.75 | 20 | empty |
| 4 | 108 | 0.36 | 0.74 | 22 | empty |
| 5 | 63 | 0.28 | 0.73 | 22 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q71EW5
- Elsewhere: RCSB PDB 2E7Z · PDBe 2E7Z · UniProt Q71EW5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.