MolNFT v1 · #35321 · protein

Crystal structure of sea domain of transmembrane protease from mus musculus

2E7V: “Crystal structure of sea domain of transmembrane protease from mus musculus”. X-ray diffraction, 1 pocket (best druggability 0.31). MolNFT v1 #35321 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2E7V
Type: protein
Length: 115 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transmembrane protease
EC: 3.4.21.-
UniProt: Q8VHK8
Pockets: 1 · best druggability 0.31

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transmembrane protease (EC 3.4.21.-)	protein	115	33% helix, 34% strand	Q8VHK8

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	53	0.31	0.76	15	empty

Compared structures

2E7V · Crystal structure of SEA domain of transmembrane protease from Mus musculus · the same entry in another collection · chain A against A, TM-score 1.00
Q8VHK8 · AlphaFold monomer V2.0 prediction for transmembrane protease serine 11D (Q8VHK8) · a predicted model of the same protein · chain A against A, TM-score 0.82

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8VHK8
Elsewhere: RCSB PDB 2E7V · PDBe 2E7V · UniProt Q8VHK8

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