MolNFT v1 · #35240 · protein

Solution structure of RNA binding domain in methenyltetrahydrofolate synthetase domain containing

2E5J: “Solution structure of RNA binding domain in methenyltetrahydrofolate synthetase domain containing”. Solution nmr, 1 pocket (best druggability 0.33). MolNFT v1 #35240 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2E5J
Type: protein
Length: 97 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Methenyltetrahydrofolate synthetase domain containing
UniProt: Q2M296
Pockets: 1 · best druggability 0.33

Structure

solution nmr · 1 distinct chain · 22% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Methenyltetrahydrofolate synthetase domain containing	protein	97	22% helix, 20% strand	Q2M296

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	78	0.33	0.75	17	empty

Compared structures

2E5J · Solution structure of RNA binding domain in Methenyltetrahydrofolate synthetase domain… · the same entry in another collection · chain A against A, TM-score 1.00
Q2M296 · AlphaFold monomer V2.0 prediction for methenyltetrahydrofolate synthase domain-containing… · a predicted model of the same protein · chain A against A, TM-score 0.73

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q2M296
Elsewhere: RCSB PDB 2E5J · PDBe 2E5J · UniProt Q2M296

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