MolNFT v1 · #35077 · protein

Dnaa N-terminal domain

2E0G · Chromosomal replication initiator protein dnaa: “Dnaa N-terminal domain”. Solution nmr, 1 pocket (best druggability 0.32). MolNFT v1 #35077 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2E0G
Type: protein
Length: 107 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chromosomal replication initiator protein dnaa
UniProt: P03004
Pockets: 1 · best druggability 0.32

Structure

solution nmr · 1 distinct chain · 35% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chromosomal replication initiator protein dnaa	protein	107	35% helix, 13% strand	P03004

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	51	0.32	0.77	14	empty

Compared structures

2E0G · DnaA N-terminal domain · the same entry in another collection · chain A against A, TM-score 1.00
P03004 · AlphaFold monomer V2.0 prediction for chromosomal replication initiator protein dnaa… · a predicted model of the same protein · chain A against A, TM-score 0.60

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03004
Elsewhere: RCSB PDB 2E0G · PDBe 2E0G · UniProt P03004

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