MolNFT v1 · #35059 · protein
Solution structure of rsgi ruh-067, a GTF2I domain in human cdna
2DZR · General transcription factor II-I repeat domain-containing…: “Solution structure of rsgi ruh-067, a GTF2I domain in human cdna”. Solution nmr, 2 pockets (best druggability 0.54). MolNFT v1 #35059 on GenesisL1: 3D structure, binding…
- PDB
- 2DZR
- Type
- protein
- Length
- 99 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- General transcription factor II-I repeat domain-containing protein 1
- UniProt
- Q9UHL9
- Pockets
- 2 · best druggability 0.54
Structure
solution nmr · 1 distinct chain · 36% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | General transcription factor II-I repeat domain-containing protein 1 | protein | 99 | 36% helix, 8% strand | Q9UHL9 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 76 | 0.54 | 0.85 | 14 | empty |
| 2 | 172 | 0.44 | 0.74 | 32 | empty |
Compared structures
- 2DZR · Solution Structure of RSGI RUH-067, a GTF2I domain in human cDNA · the same entry in another collection · chain A against A, TM-score 1.00
- Q9UHL9 · AlphaFold monomer V2.0 prediction for general transcription factor II-I repeat… · a predicted model of the same protein · chain A against A, TM-score 0.73
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UHL9
- Elsewhere: RCSB PDB 2DZR · PDBe 2DZR · UniProt Q9UHL9
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