MolNFT v1 · #35022 · protein

Crystal structure of the N-terminal domain of mouse galectin-4

2DYC: “Crystal structure of the N-terminal domain of mouse galectin-4”. X-ray diffraction, 1 pocket (best druggability 0.30). MolNFT v1 #35022 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2DYC
Type: protein
Length: 147 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Galectin-4
UniProt: Q8K419
Pockets: 1 · best druggability 0.30

Structure

x-ray diffraction · 1 distinct chain · 2% helix, 52% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Galectin-4	protein	147	2% helix, 52% strand	Q8K419

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	53	0.30	0.76	16	empty

Modifications

Observed in the structure: 8 modified (engineered).

Compared structures

2DYC · Crystal structure of the N-terminal domain of mouse galectin-4 · the same entry in another collection · chain A against A, TM-score 1.00
Q8K419 · AlphaFold monomer V2.0 prediction for galectin-4 (Q8K419) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8K419
Elsewhere: RCSB PDB 2DYC · PDBe 2DYC · UniProt Q8K419

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